Sulforaphane and isothiocyanate goitrogen concerns | Rhonda Patrick
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Broccoli sprouts are concentrated sources of sulforaphane, a type of isothiocyanate. Damaging broccoli sprouts – when chewing, chopping, or freezing – triggers an enzymatic reaction in the tiny plants that produces sulforaphane.
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Some concerns have arisen that sulforaphane, an isothiocyanate compound derived from certain cruciferous vegetables, may disrupt thyroid hormone function and potentially act as a goitrogen by competing with iodine uptake. Long-term studies in iodine-deficient or hypothyroid animals showed no ill effects with high dose sulforaphane supplementation, however. While iodine deficiency is rare, a person considering sulforaphane supplementation should consult their physician to have their thyroid hormone levels monitored. In this clip, Dr. Rhonda Patrick describes the potential interaction between sulforaphane and iodine and stresses that iodine-deficient people or those with hypothyroidism should work with their physician to monitor thyroid hormone levels.
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Sulforaphane News
- Sulforaphane extends lifespan and healthspan in worms via insulin and insulin-like growth factor-1 signaling.
- Paul Saladino, MD explains how we may have overstated the health benefits of plants and especially sulforaphane
- NRF2 much of a good thing (December 2017)
- A pilot trial finds sulforaphane treatment increased glutathione levels in the blood & hippocampus region of the brain in healthy people.
- A new study found sulforaphane (found in broccoli sprouts) improved behavior & social responsiveness in children with autism.
