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In animal studies, high doses of magnesium in the form of magnesium L-threonate have been shown to cross the blood-brain barrier readily and coincide with improvements in cognitive function. One clinical study in humans showed a high dose of magnesium L-threonate resulted in marginal improvements in cognitive function. However, plasma and red blood cell magnesium levels increased minimally or not at all, with much being excreted in the urine. In this clip, Dr. Rhonda Patrick explains that while magnesium L-threonate has yielded promising results in animal studies, this has yet to be translated to humans.
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