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Living longer and healthier doesn't require extreme behaviors. Eating right, moving more, and managing stress are just a few of the habits, especially in midlife, that predict telomere length. In this clip, Dr. Elissa Epel describes the "low hanging fruit" – small, healthy lifestyle behaviors – that can have positive effects on telomere length and lifespan.
Elissa: It's a whole formula. So it's not one thing. Like, the levers that control aging are the things that we know about but we easily forget. So we often hear, you know, about the lifestyle things. So activity, nutrition, stress. So those are really important to manage well, and they add up over time. So like a healthy lifestyle, not extreme but just healthy, in midlife predicts longer telomeres, predicts longevity decades later.
So we don't need to be extreme about this. We just need to really notice the toxic things we're doing. You know, like smoking, and sitting too much, and you know, leaving stress unchecked, and just having years and years of feeling vigilant and not getting enough sleep. So there's a lot of low hanging fruit that we know about.
Distinctive structures comprised of short, repetitive sequences of DNA located on the ends of chromosomes. Telomeres form a protective “cap” – a sort of disposable buffer that gradually shortens with age – that prevents chromosomes from losing genes or sticking to other chromosomes during cell division. When the telomeres on a cell’s chromosomes get too short, the chromosome reaches a “critical length,” and the cell stops dividing (senescence) or dies (apoptosis). Telomeres are replenished by the enzyme telomerase, a reverse transcriptase.
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