How to make cells permanently immune to all viruses │ Dr. George Church
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In 2022, Dr. George Church and his research team published the results of an experiment in which they used gene editing to make E. coli cells resistant to infection by all viruses. The number of genome edits required to achieve this was large enough that synthesizing the entire E. coli genome from scratch was the more feasible option. Genetically recoded organisms could revolutionize public health by limiting the transmission of diseases from livestock animals to humans, called zoonotic infections. Dr. Church and colleagues demonstrated in a second 2022 publication that CRISPR germline editing could be used to eliminate African Swine Fever virus in pigs. In this clip, Dr. George Church discusses these findings and what they could mean for the future of public health.
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