Wim Hof’s personal connection to depression and the historical use of cold as a treatment
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Cold baths have been used as a therapy for depression for more than 100 years. The Dutch artist Vincent van Gogh, while in an asylum, was prescribed two cold baths a day. The body releases chemicals in response to cold exposure and specific breathing techniques that act to suppress inflammatory cytokines. Reducing inflammation may be beneficial for a variety of physical and mental conditions. In this clip, Wim Hof shares his personal story that led to his passionate pursuit of how we can harness the body's innate ability to heal itself.
Rhonda: Very, very cool. I would love to see, you know, this, like I said, potentially be used to help treat depression, to help treat a lot of...
Wim: Oh yes, depression. It's my next thing.
Rhonda: ...inflammatory.
Wim: My wife died because of being schizophrenic, as they say. Like no control. And I saw there was no control. I lost her, and I have four kids with her. That's the way I began to have interest in scientific studies to show we are able to do so much more. It's in there. It's a soul search. And that's the way I began.
Rhonda: Do you think that Holland may be open to this type of treatment? And the reason I say this is because, just a couple of days ago, I was at the Van Gogh Museum, you know, I'm a tourist, and going to the Van Gogh Museum, and we're all kind of drawn to van Gogh, because he has got this dark story, he cut off his ear, he killed himself.
Wim: Same thing. Same thing.
Rhonda: Yeah. And as I was reading through...you know, looking at his paintings and reading through, you know, the history behind it...
Wim: Emotions and all that, yeah. It's real.
Rhonda: Yeah. Well then, what happened was he went to this sort of psychiatric hospital, and I thought immediately, "Oh, they probably put him on drugs." I mean, that's what I thought. As I was reading, it said, "No, his prescription was two cold baths a day."
Wim: Look at that.
Rhonda: And that... I was... I mean, I looked at my husband, and I was like, "Are you kidding me? Is this really, you know..." So is that something you think that maybe... You know, because this was in the Netherlands.
Wim: Yes. Actually it was in the south of France with van Gogh.
Rhonda: Oh, was it in the south of France? I thought you said, oh, okay...
Wim: Yeah, but he was so depressed, and the light has got a lot of influence on depression. Melatonin, serotonin, the hormone production, etc. So he went to the south of France finally, and then Arles, somewhere south of France, he got into this psychiatric asylum, but they didn't know as well. Because the cold brings about the alarm cells in the body, which suppresses the cytokine production direct, but then the breathing even does more.
Rhonda: Yeah. Norepinephrine is increased by the cold, and it suppresses the cytokine production, but the epinephrine from the breathing does it even more robust. But I was so curious that back in the late 1800s they were saying cold bath. Why not now?
Wim: You are the first one to tell me he took a bath.
Rhonda: Twice a day.
Wim: I've lost my respect for Vincent van Gogh, who was a crazy motherfucker. I'm sorry.
Rhonda: It's okay.
Wim: We cannot say that. But he cut off his ear, and then shot himself. And my wife, you're like 200 years later, jumped from 8th floor, having 4 children. I'm working with the children right now, and we're having a great company, and we got a lot of happiness and all that, but those days we had a lot of discomfort and no power and being dependent on all these systems, and that's why I say, sorry about the F word, but it's the F word, these systems, F these systems, because we are going to do something about this. And this time we're going to bring back the belief, but also the real chemical connection within the body and the brain toward all the people. And that's regarding depression, any type of mental disorder or physical disorder.
Rhonda: Yeah. Inflammatory disorders in general.
Wim: Yes, inflammation. Cytokine production. Are we able to tap into that? Yes. Are we able to tap into the vagus nerve? Yes. Are we able to tap into the autonomic nervous system? Yes. I'm sorry, yes.
Rhonda: Please keep doing what you're doing, and, you know, it's awesome, your passion, your energy and what you're doing, I respect.
Wim: And likewise.
Rhonda: Thank you.
Wim: I respect your work, which is very good, and it is really needed.
A division of the peripheral nervous system that influences the function of internal organs. The autonomic nervous system regulates bodily functions that occur below the level of consciousness, such as heart rate, digestion, respiratory rate, pupillary response, urination, and sexual arousal. It is the primary mechanism in control of the fight-or-flight response and the freeze-and-dissociate response.
A broad category of small proteins (~5-20 kDa) that are important in cell signaling. Cytokines are short-lived proteins that are released by cells to regulate the function of other cells. Sources of cytokines include macrophages, B lymphocytes, mast cells, endothelial cells, fibroblasts, and various stromal cells. Types of cytokines include chemokines, interferons, interleukins, lymphokines, and tumor necrosis factor.
A mood disorder characterized by profound sadness, fatigue, altered sleep and appetite, as well as feelings of guilt or low self-worth. Depression is often accompanied by perturbations in metabolic, hormonal, and immune function. A critical element in the pathophysiology of depression is inflammation. As a result, elevated biomarkers of inflammation, including the proinflammatory cytokines interleukin-6 and tumor necrosis factor-alpha, are commonly observed in depressed people. Although selective serotonin reuptake inhibitors and cognitive behavioral therapy typically form the first line of treatment for people who have depression, several non-pharmacological adjunct therapies have demonstrated effectiveness in modulating depressive symptoms, including exercise, dietary modification (especially interventions that capitalize on circadian rhythms), meditation, sauna use, and light therapy, among others.
A critical element of the body’s immune response. Inflammation occurs when the body is exposed to harmful stimuli, such as pathogens, damaged cells, or irritants. It is a protective response that involves immune cells, cell-signaling proteins, and pro-inflammatory factors. Acute inflammation occurs after minor injuries or infections and is characterized by local redness, swelling, or fever. Chronic inflammation occurs on the cellular level in response to toxins or other stressors and is often “invisible.” It plays a key role in the development of many chronic diseases, including cancer, cardiovascular disease, and diabetes.
A hormone that regulates the sleep-wake cycle in mammals. Melatonin is produced in the pineal gland of the brain and is involved in the expression of more than 500 genes. The greatest influence on melatonin secretion is light: Generally, melatonin levels are low during the day and high during the night. Interestingly, melatonin levels are elevated in blind people, potentially contributing to their decreased cancer risk.[1]
A substance produced in the brain. Norepinephrine acts as a hormone and neurotransmitter and is best known for its role in the body’s “fight or flight” response to stress. Its role as a neurotransmitter has been exploited as a molecular target for a class of drugs known as norepinephrine reuptake inhibitors, which were developed for the purpose of treating disorders ranging from ADHD to narcolepsy and depression. Norepinephrine also plays a role in converting white adipose tissue into brown adipose tissue via an uncoupling protein 1 (UCP-1) mediated mechanism.
A small molecule that functions as both a neurotransmitter and a hormone. Serotonin is produced in the brain and gut and facilitates the bidirectional communication between the two. It regulates many physiological functions, including sleep, appetite, mood, thermoregulation, and others. Many antidepressants are selective serotonin reuptake inhibitors (SSRIs), which work by preventing the reabsorption of serotonin, thereby increasing extracellular levels of the hormone.
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