Aliquot #6: Genetic and lifestyle risk factors for Alzheimer's disease
Aliquot #6: Genetic and lifestyle risk factors for Alzheimer's disease
Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk. These Aliquot segments feature Dr. Dale Bredesen, a professor of neurology, and Dr. Matthew Walker, a professor of neuroscience and psychology.
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Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk. These Aliquot segments feature Dr. Dale Bredesen, a professor of neurology, and Dr. Matthew Walker, a professor of neuroscience and psychology.
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Introduction
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ApoE4 increases Alzheimer’s disease risk, but healthy habits can reduce risk (Dale Bredesen discussion)
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People who are ApoE4+ have 2x the risk of having sleep apnea (Matthew Walker segments)
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Glial cells are the sewage system for the brain
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