Biodistribution in different organs of the Pfizer BioNtech mRNA COVID-19 vaccine | Dr. Rhonda Patrick

Posted on October 1st 2021 (over 3 years)

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COVID-19 mRNA vaccines consist of a small piece of mRNA protected by a lipid droplet that is injected into the deltoid muscle of the arm. The spike protein is made and expressed on the cell's surface where it remains until it is detected by the immune system. There has been some concern — stemming from studies in rodents given massive doses — that vaccine nanoparticles can exit the deltoid muscle and travel to other organs. When researchers gave rats a human-equivalent dose no vaccine particles were observed after 48 hours. Furthermore, these initial studies did not distinguish between intact vaccine particles, remnants, or merely tagging molecules. In this clip, Dr. Rhonda Patrick discusses whether mRNA COVID-19 vaccines spread to different organs.

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