My interest is definitely piqued. The animal evidence is exciting too. That said, I do worry about some of the changes they observed in cholesterol (although I think that was due to pterostilbene). It might not be that worthy of concern (there’s more to heart disease than just total LDL), but, in general, I’d still like to see more evidence.
I realize that this doesn’t answer your questions directly. They’re good ones, but I don’t have all of the answers.
That’s good to hear the animal evidence looks exciting, and hopefully the cholesterol observations aren’t an issue.
Elysium Health seem to be on the right path. (Still always skeptical of a company funding/doing research on their own products)
But they were very responsive on twitter relating to this study and their desire to look into taking human biopsies in future clinical trials to answer if NAD concentrations actually increase in the mitochondria vs circulating in the blood/tissues.
Regarding the funding issue: that’s true, but this issue is definitely mitigated by the impact factor of the journal IMO. A Nature paper is pretty top shelf.
They’re definitely doing Twitter right… I think the Twitter thread to which you’re referring shows a desire to talk to the actual science. I was impressed, anyway.
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Definitely very interesting. Does this mean that taking this combo (which is the Basis product by Elysium) a good way to try to stave off aging?
Is it something that is worth taking if you are younger than the population in the trial (men and women ages 60 - 80)
Edit: also, how do these effects compare to a combo with regular (cheap and not patented) B3?
My interest is definitely piqued. The animal evidence is exciting too. That said, I do worry about some of the changes they observed in cholesterol (although I think that was due to pterostilbene). It might not be that worthy of concern (there’s more to heart disease than just total LDL), but, in general, I’d still like to see more evidence.
I realize that this doesn’t answer your questions directly. They’re good ones, but I don’t have all of the answers.
Anyone considering buying from Elysium should think twice. Here is why: https://www.right-of-assembly.org/single-post/2017/08/16/Why-I-Feel-Suckered-by-Elysium-Health
I personally went with Thorne (Tru Niagen carries a 25% import duty where I live or I would have opted for those).
That’s good to hear the animal evidence looks exciting, and hopefully the cholesterol observations aren’t an issue.
Elysium Health seem to be on the right path. (Still always skeptical of a company funding/doing research on their own products)
But they were very responsive on twitter relating to this study and their desire to look into taking human biopsies in future clinical trials to answer if NAD concentrations actually increase in the mitochondria vs circulating in the blood/tissues.
Definitely an area to keep on my radar.
Regarding the funding issue: that’s true, but this issue is definitely mitigated by the impact factor of the journal IMO. A Nature paper is pretty top shelf.
They’re definitely doing Twitter right… I think the Twitter thread to which you’re referring shows a desire to talk to the actual science. I was impressed, anyway.