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    I typically intermittent fast/TRE regularly (only feeding between the hours of 10am-7pm) but just found out that I’m pregnant. As of yet, I haven’t felt much change in appetite (I eat a low carb, whole food diet based on low carb leafy greens and veggies, eggs, fatty fish, nuts, avocados, MCT oil, etc) but wonder if it is contraindicated somehow to continue to time restrict when I feed. Did you continue to follow your time restricted eating habits while your were pregnant? Based on the many podcasts I’ve been listening to, it doesn’t sound like I need to change much about the content of my food, just increase the caloric content in a few months by a few hundred calories. If I can handle it, I don’t see why I’d alter my eating window. Just curious on your thoughts, Dr. Patrick. Thanks, Elizabeth

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      I’ve tried TRE many times over the years and I really do enjoy it especially when cutting down or when I have a hectic schedule. Now I really want to try and gain the benefits for longevity from fasting, but I’ve been unsuccessful in finding a real answer about fasting and medication/supplements. I am curious to know if my thyroid medication and pre work supplements count as ending my fast as I like to workout after waking up and don’t eat until a few hours later. Any help is much appreciated! Thank you!!

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        I started intermittent fasting at the beginning of the year and have found great success with it. I usually start the day and only drink water for the first 4-5 hours of the day and occasionally a cup of black coffee. I typically drink water with electrolytes with a ph of around 8. My question is will it break my fast if I add the juice from a lemon wedge and some sea salt to my water? Any information is greatly appreciated.

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          Rhonda, are you aware of Dr. Panda’s view on supplementation during prolonged 4-5 day water fasts? Is it necessary to replenish sodium, magnesium and potassium, or supplement with amino acids to avoid severe lean tissue loss? Thanks, wonderful episode and so glad you dived into this topic for us.

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            Hi Dr.Patrick, I know you’ve been doing TRE for a while, how do you manage hunger? This is so hard! does your body get used to it eventually and hunger subsides?

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              Hi Rhonda - in your podcast with Joe Rogan you mentioned that even taking vitamins in the morning can stimulate your appetite and thus doesn’t count as fasting. Does birth control have the same effect?

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                Hello Rhonda,

                First of all I want to say I’m a big fan of your work and it’s all benefitted me a lot. Now I am an athlete and I have come across a rather tricky scenario. I try to stick to the TRF but I am an athlete and I do a lot of strength training, as well as my actual sport. Now I’m finding myself having difficulty managing my recovery when i have such a short time span to eat. By the time I finish my practice it is dark outside, but if i do not eat after practice my recovery is shot. Is there any information on activity level correlating to keeping the metabolism going after dark?

                I know you’re a busy person, and have other things to worry about. But it would shine a light on a dilemma for athletes.

                Thanks

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                  @Rhonda: This is great info, I’m specifically wondering about whether drinking salt water (Pink Himalayan Salt) would break the fast cycle?

                  I do my 1st workout @4am and while i don’t do pre-workouts I do 24oz. of water + 1tsp of Pink Himalayan Sea Salt. I’ve found that this aids in getting hydrated post sleeping for 6-8hrs.

                  My understanding is that salt is a mineral and does not get digested.

                  I have the same question about allergy medications, psyllium husk(with water & cinnamon) and supplements. I take omega-3 fish oils in the morning as well as Allclear (kirland/costco brand claratin)

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                    Rhonda, fascinating info. I’ve started a 14/10 (or is it 10/14?) fast based on this info. However, One thing that is not clear to me is the effect of medications on the fasting period. I take daily Aloopurinol for gout, occasional ibuprofen for pain releif, and occasional Clonazepam as a sleep aid. Will taking any of these medications break the fast? I’ve scoured the internet but have been unable to find any information that is definitive on this.

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                      I have been wondering about the effect of medications too. Also,is it an ‘all or nothing’ type effect- for example, does ingesting tea (for example) start the clock in the same way as a big breakfast?

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                      Rhonda, Thank you for the time and effort you put into giving detailed evidence-based information that can be applied by people who aren’t so connected to the current research. I really enjoyed the podcasts with Dr. Panda. I looked a bit more into the study you mention at 1:07:00 concerning surgery outcomes based on time of surgery. I looked for the study you mentioned but the one that was linked I don’t believe was the correct study. The one linked was this one: https://www.nature.com/articles/nrgastro.2010.156 which is about surgery outcomes of humans based on time of day. It seems it is getting more at the performance of the surgeons based on time of day versus the circadian effect that you mentioned in the podcast in the mouse study. I find the concept fascinating and would like to read more on it if you have those studies available. Thanks again for all you do!

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                        I am confused by the idea that consuming anything with calories will start the circadian clock and cut short the intermittent fasting time.

                        What happens to a person’s circadian rhythm during a multi-day water fast? If his rhythm remains unaltered (because he still gets up at the same time, is active during the day, and retires at the same time at night) then can we also assume that his circadian rhythm is likewise unaltered during a period of fast mimicking? Dr. Longo’s fast mimicking calls for a daily intake of at least 700 kcal. If the body thinks it is fasting, even with this level of nutritional intake, why would the circadian rhythm clock be affected any differently than in a water fast? And even if it does start a circadian rhythm clock, why would it affect the benefits accruing to the body as a result of the fast?

                        And this brings us to daily intermittent fasting. If a person has an actual eating window of, say, 9 hours but the window does not start until four hours after he arises for the day, how can drinking coffee, even with fat, or tea, or hot water with lemon juice, etc., break the fast when these things are not cognizable by the body during fast mimicking? And why would the intake of these few calories cause the start of a circadian clock effectively nullifying the benefits of the intermittent fast? In other words, if a few calories do not break a long fast, why would they break a short fast?

                        This is confusing.

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                          Thank you so much Rhonda for bringing us this amazing information! You and Dr. Panda were discussing improved endurance performance with the TRE protocol and intermittent fasting. Are there any human studies or animal studies you know of were this is seen?

                          Keep up the great work! Betsy

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                            Thanks, Betsy! There is indeed some human evidence that fasting, in some contexts, improves endurance and muscle mass.

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                            As always, phenomenal content. On top of that, stellar website layout! Congrats on this great improvement, keep up the extraordinary work Rhonda.

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                              Thanks! Satchin is doing such important research…always glad to catch up with what his latest research is. Glad you like the website redesign. Lot’s more cool stuff to come! :)